The most common non-opioid medications that can be helpful in managing chronic pain include acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs) like celecoxib (Celebrex and generics) and many other prescription drugs in this category, and over the counter ibuprofen and naproxen (Motrin, Aleve, and generics). Some patients may benefit from adding antidepressants such as amitriptyline or venlafaxine; others may find adding gabapentin or pregabalin is helpful for nerve pain. There are others that are generally only used if none of the above are helpful or have caused intolerable side effects. Medical cannabis (marijuana), as we just mentioned, also fits in this category, and is helpful for chronic pain in some patients. We are learning much more about cannabis with new research.
Terri, are there any alternative medications to opioids, whether prescription or over the counter medications, that can be helpful for some people with chronic pain?
This is a difficult situation, for sure. Some of the newer opioids that have other actions than the usual opioid effects might be more helpful, but this is hard to predict. The ones I have in mind here are tramadol and tapentadol, that have some minor effects that are similar to some of the antidepressants. Having said that, for some people the side effects may be worse, or just as bad, but different - in other words not any better.
It has certainly become more common, especially in the last year or so, for people in pain who don't tolerate opioids very well to look into medical marijuana as an option. It can be a challenge to find physicians who are comfortable with recommending and authorizing it, and experienced in prescribing it so they can advise you on how to choose products and what doses to start with. But, if trying new opioids has not been helpful, this may be worth considering if you can get access to good medical advice.
How long should I keep trying different opioids? It's hard to know whether I just have to put up with the side effects or if there's another, better opioid I could be using?
Are there any opioid medications with fewer side effects?
Great, thanks for answering the first 2 questions Terri. Another question we received in advance asks if you can go over some of the common side effects of opioid medications.
How do I find a good pharmacist?
Hello, everyone, I'm happy to be here and ready to do my best at answering your questions about medications, pharmacies and pharmacists.
Welcome Terri! We're very thrilled to have you on today's Ask the Expert live forum discussion. Let's get started. Here's a question that was submitted to us in advance: besides dispensing medications, what can a pharmacist do for a person in pain?
Good morning and hello to everyone joining us on today's Ask the Expert series, where you'll be able to live chat with clinical pharmacist Terri Betts regarding your pain-related questions. We will be getting started in approximately 15 minutes.